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03530nam a2200433 4500 |
| 001 |
ocn828711117 |
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OCoLC |
| 005 |
20180501122007.0 |
| 006 |
m o d |
| 007 |
cr mnu---uuaaa |
| 008 |
130218s2013 caua ob 001 0 eng |
| 040 |
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|a AU@
|b eng
|e pn
|c AU@
|d E7B
|d OCLCO
|d OCLCQ
|d CUS
|d UIU
|d OPELS
|d OCLCF
|d KUK
|d OCLCQ
|d AZS
|d OCLCQ
|d OCLCA
|d CASUM
|d OCLCO
|d MERER
|d OCLCO
|d OCLCQ
|d OCLCA
|d GrThAP
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| 020 |
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|a 9780124078659
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| 020 |
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|a 0124078656
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| 035 |
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|a (OCoLC)828711117
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| 050 |
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4 |
|a QP552.G16 .G384 2013
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| 082 |
0 |
4 |
|a 572/.696
|2 23
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| 049 |
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|a TEFA
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| 245 |
0 |
0 |
|a G protein coupled receptors.
|p Modeling, activation, interactions and virtual screening /
|c edited by P. Michael Conn.
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| 246 |
3 |
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|a Modeling, activation, interactions and virtual screening
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| 260 |
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|a San Diego, Calif. :
|b Academic,
|c 2013.
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| 300 |
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|a 1 online resource (lvi, 472 pages) :
|b illustrations.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in enzymology,
|x 0076-6879 ;
|v v. 522
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| 504 |
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|a Includes bibliographical references and indexes.
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| 505 |
0 |
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|a The protein local optimization program and g-protein-coupled receptors:loop restoration and applications to homology modeling -- Modeling active GPCR conformations -- Molecular modeling of adenosine receptors -- Predicting g-protein-coupled receptors families using differet physiochemical properties and pseudo amino acid composition -- Computational design and experimental characterization of GPCR segment models -- G-protein-coupled receptor interaction with small GTPases -- Quantification of receptor tyrosine kinase activiation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SplDA) -- NMR modeling for detection of small molecule binding to RGS4 -- Group II activators of g-protein signaling: monitoring the interaction of G[alpha] with G-protein motif in the intact cell -- Homogenous time-resolved fluorescence assay to probe folded G protein-coupled receptors -- cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors -- Rhodospin-lipid intereactions studied by NMR -- Biasing the parathyroid hormone receptor: relating in vitro ligand efficacy to in vivo biological activity -- Application of Monte Carlo-based receptor ensemble docking to virtual screening for GPCR ligands -- From heptahelical bundle to hits from the haystack: structure-based virtual screening for GPCR ligands -- Kinetics and dynamics in the G protein-coupled receptor signaling cascade -- Magic angle spinning nuclear magnetic resonance spectroscopy fo G protein-coupled receptors -- Posttranslation modification of G protein-coupled receptor in relationship to biased agonism -- Protein S-nitrosylation measurement.
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| 650 |
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0 |
|a Cell receptors
|x Structure-activity relationships.
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| 650 |
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0 |
|a G proteins
|x Receptors.
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| 650 |
|
7 |
|a Cell receptors
|x Structure-activity relationships.
|2 fast
|0 (OCoLC)fst00850232
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| 650 |
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7 |
|a G proteins
|x Receptors.
|2 fast
|0 (OCoLC)fst00936832
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| 650 |
1 |
2 |
|a Receptors, G-Protein-Coupled
|x analysis.
|0 (DNLM)D043562Q000032
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| 650 |
1 |
2 |
|a Receptors, G-Protein-Coupled
|x physiology.
|0 (DNLM)D043562Q000502
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| 650 |
2 |
2 |
|a Magnetic Resonance Spectroscopy.
|0 (DNLM)D009682
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Conn, P. Michael.
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| 830 |
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0 |
|a Methods in enzymology ;
|v v. 522.
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| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00766879/522
|z Full Text via HEAL-Link
|