Clinical trial design : Bayesian and frequentist adaptive methods /
There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This bo...
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| Format: | eBook |
| Language: | English |
| Published: |
Hoboken, N.J. :
John Wiley & Sons,
[2012]
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| Series: | Wiley series in probability and statistics.
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| Online Access: | Full Text via HEAL-Link |
| Summary: | There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This book provides an overview of the fundamentals of clinical trials, the key terminologies and concepts, and a brief review and comparison on Bayesian and frequentist estimation and inference procedures. From the practical point of view, this book introduces various statistical methods that are commonly. |
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| Physical Description: | 1 online resource (xvii, 336 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and indexes. |
| ISBN: | 9781118183335 1118183339 9781118183304 1118183304 |
| DOI: | 10.1002/9781118183335 |
