Modelling Proteasome Dynamics in a Bayesian Framework

Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experi...

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Bibliographic Details
Main Author: Stübler, Sabine (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:English
Published: Wiesbaden : Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum, 2017.
Series:BestMasters
Subjects:
Online Access:Full Text via HEAL-Link
Table of Contents:
  • Structure and Function of the Proteasome
  • Approaches to Model Proteasome Dynamics
  • Comparison of the Dynamics of Proteasome Subtypes
  • Inhibitor Influence on the Catalytic Subunits
  • Inhibitor Influence on a Compartmentalised Short Fluorogenic Peptide Model .  .