Modelling Proteasome Dynamics in a Bayesian Framework
Sabine Stübler compares different proteasome isoforms and subtypes in terms of their transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in in vitro experi...
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Format: | Electronic eBook |
Language: | English |
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Wiesbaden :
Springer Fachmedien Wiesbaden : Imprint: Springer Spektrum,
2017.
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Series: | BestMasters
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Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Structure and Function of the Proteasome
- Approaches to Model Proteasome Dynamics
- Comparison of the Dynamics of Proteasome Subtypes
- Inhibitor Influence on the Catalytic Subunits
- Inhibitor Influence on a Compartmentalised Short Fluorogenic Peptide Model . .