Phosphoinositide 3-kinase in Health and Disease Volume 1 /
From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in pro...
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| Other Authors: | , , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg :
Springer Berlin Heidelberg : Imprint: Springer,
2011.
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| Series: | Current Topics in Microbiology and Immunology,
346 |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
| Summary: | From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here. |
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| Physical Description: | X, 310 p. 29 illus., 23 illus. in color. online resource. |
| ISBN: | 9783642136634 |
| ISSN: | 0070-217X ; |
