Delta Opioid Receptor Pharmacology and Therapeutic Applications
This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds an...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Cham :
Springer International Publishing : Imprint: Springer,
2018.
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| Edition: | 1st ed. 2018. |
| Series: | Handbook of Experimental Pharmacology,
247 |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
| Summary: | This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states. Part 1 covers the endogenous ligands that regulate the DOR system as well as novel compounds and therapies used to modulate the DOR system. Part 2 describes new insights into the localization and trafficking of the DOR and how ligand-directed signaling alters the fate of the receptor. Part 3 concentrates on the potential role of the DOR system in disease states, such as pain, mood, addiction, and Parkinson's disease. Throughout the book, the DOR system as a target for drug development will be discussed. |
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| Physical Description: | VIII, 345 p. online resource. |
| ISBN: | 9783319951331 |
| ISSN: | 0171-2004 ; |
| DOI: | 10.1007/978-3-319-95133-1 |
