The Inflammasomes
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene,...
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| Other Authors: | , , |
| Format: | Electronic eBook |
| Language: | English |
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Basel :
Springer Basel,
2011.
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| Series: | Progress in Inflammation Research
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| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Molecular definition of inflammasomes
- Pyroptosis: A Caspase-1-dependent programmed cell death and a barrier to infection
- Activation of the inflammasome by bacterial pathogens
- The Role of Inflammasomes in Viral Infection
- Inflammasome activation in response to eukaryotic pathogens
- Inflammasome activation by pathogenic crystals and particles
- Inflammasome activation by danger signals
- Toll like receptors and inflammasomes
- Inflammasome in the skin
- Cancer, inflammasomes and adjuvanticity
- Inflammasome and lung pathologies
- Mechanisms of NLRP3 inflammasome activation in CAPS patients
- Activation and regulation of the NLRP3 inflammasome
- Treatment of inflammasome-related disorders.
